Anesthesia for endoscopy.
Conditions
Interventions
Intervention 1: Intervention group: In dexmedetomidine group (Dk), patients will receive 1-0. 7 micrograms per kilogram of dexmedetomidine and then bolus ketamine 0.4 mg per kilogram in 50 ml of norm
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
2 Years to 12 Years
Inclusion criteria
Inclusion criteria: Consent of the patient or parents to participate in the study Patients aged 2 to 12 years
Exclusion criteria
Exclusion criteria: ventricular atrial block (Grade 2 or 3 ) in electrocardiography Slow heart rate QTc more than 550 Millisecondon electrocardiography Severe heart failure low blood pressure (systolic blood pressure less than 90 mmHg or diastolic blood pressure less than 60 mmHg) Liver disease Use of any analgesic drug (due to possible drug interactions with the two drugs used in the study and the possibility of influencing the conclusion and prejudice of anesthesia) History of any allergy to the drug used in the design (dexmedetomidine and propofol)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sedation depth. Timepoint: Every 5 minutes during procedure and every 10 minutes in recovery. Method of measurement: Ramsey Sedation criteria. | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood pressure. Timepoint: Before intervention, every 5 minutes after the intervention and every 10 minutes after the end of the intervention for 30 minutes. Method of measurement: Blood pressure barometer.;Heart rate. Timepoint: Before intervention, every 5 minutes after the intervention and every 10 minutes after the end of the intervention for 30 minutes. Method of measurement: Pulse oximeter.;Recovery time. Timepoint: After completing the intervention until the withdrawal from the recovery. Method of measurement: Minute Numbers.;Surgery time. Timepoint: From the beginning of the surgery. Method of measurement: Minute Numbers.;Duration of anesthesia. Timepoint: From the time of anesthesia injection to the time of consciousness. Method of measurement: Minute Numbers.;Complications (bradycardia, apnea). Timepoint: Before intervention, every 5 minutes after the intervention and every 10 minutes after the end of the intervention for 30 minutes. Method of measurement: Monitoring.;Incidence of complications in recovery. Timepoint: Every 10 minutes after the end of the intervention for 30 minutes. Method of measurement: Patient monitoring and observation. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHamidreza Shetabi
Esfahan University of Medical Sciences
Outcome results
None listed