Relaxation of Ketamine Propofol and Fentanyl Propofol in Cataract Surgery

Comparison of sedative efficacy of ketamine propofol 1 to 3 and fentanyl propofol in cataract surgery by phacoamulsification method

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180416039326N2

Enrollment

100

Registered

2018-07-18

Start date

2017-03-21

Completion date

Unknown

Last updated

2018-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cataract surgery. Unspecified disorder of vitreous body

Interventions

Intervention 1: Intervention group: first: the combination of Ketamine- propofol.Syringe 2 contains pethidine (0.2 mg / kg) with distilled water at a concentration of 5cc (concentration 10mg / cc). Pr

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients undergoing cataract surgery by phacoamulsification

Exclusion criteria

Exclusion criteria: .History of any allergy to anesthetic drugs Congestive Heart Failure Cardiac arrest Glaucoma Hypotension Chronic respiratory disease Psychosis Schizophrenia

Design outcomes

Primary

Measure	Time frame
Sedation level based on ramsay score. Timepoint: Immediately before surgery, every 5 minutes during and after surgery every 10 minutes for 30 minutes in recovery. Method of measurement: Ramsay score.	—

Secondary

Measure	Time frame
Arterial pressure. Timepoint: Immediately before surgery, every 5 minutes during and after surgery every 10 minutes for 30 minutes in recovery. Method of measurement: Pressure gauge.;Heart rate. Timepoint: Immediately before surgery, every 5 minutes during and after surgery every 10 minutes for 30 minutes in recovery. Method of measurement: Oximetry pulse.;Surgeon Satisfaction. Timepoint: Immediately before surgery, every 5 minutes during and after surgery every 10 minutes for 30 minutes in recovery. Method of measurement: Likert questionnaire.;Percent saturation of oxygen. Timepoint: Immediately before surgery, every 5 minutes during and after surgery every 10 minutes for 30 minutes in recovery. Method of measurement: Oximetry pulse.	—

Measure

Time frame

Arterial pressure. Timepoint: Immediately before surgery, every 5 minutes during and after surgery every 10 minutes for 30 minutes in recovery. Method of measurement: Pressure gauge.;Heart rate. Timepoint: Immediately before surgery, every 5 minutes during and after surgery every 10 minutes for 30 minutes in recovery. Method of measurement: Oximetry pulse.;Surgeon Satisfaction. Timepoint: Immediately before surgery, every 5 minutes during and after surgery every 10 minutes for 30 minutes in recovery. Method of measurement: Likert questionnaire.;Percent saturation of oxygen. Timepoint: Immediately before surgery, every 5 minutes during and after surgery every 10 minutes for 30 minutes in recovery. Method of measurement: Oximetry pulse.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamidreza Shetabi

Esfahan University of Medical Sciences

hamidshetabi@med.mui.ac.ir+98 31 3668 8138

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026