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Comparison of cardiovascular response to laryngoscopy and endotracheal intubation in induction of anesthesia with etomidate and thiopental sodium - Midazolam

Evaluation and comparison of cardiovascular response to laryngoscopy and endotracheal intubation in induction of anesthesia with etomidate and thiopental sodium - Midazolam

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180416039326N11
Enrollment
78
Registered
2020-03-14
Start date
2020-03-04
Completion date
Unknown
Last updated
2020-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular response. T88.5

Interventions

Intervention 1: First intervention group: after receiving 5 ml/kg of ringer lactate and pre-oxygenation for patients, induction of anesthesia was performed including Fentanyl 2mcg/kg, Etomidate 0.3mg/

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients who are candidates for short-term elective surgery (less than2 hours) under general anesthesia Age between 18 to 70 years old ASA1&2

Exclusion criteria

Exclusion criteria: Obese patients Pregnant women Uncontrolled diabetic patients Uncontrolled COPD patients Uncontrolled cardiovascular patients Chronic analgesic or sedative use BMI more than 25 kg/m2 Any Uncontrolled systemic disease Predicting the difficulty of airway protection Any sensitivity or allergies to the anesthetics agent used

Design outcomes

Primary

MeasureTime frame
Heart rate. Timepoint: Basic time, minutes 1 and 3 after induction and minutes 1, 3, 5 and 10 after intubation. Method of measurement: Electrocardiogram (EKG).;Blood pressure. Timepoint: Basic time, minutes 1 and 3 after induction and minutes 1, 3, 5 and 10 after intubation. Method of measurement: Barometer.;Mean arterial pressure. Timepoint: Basic time, minutes 1 and 3 after induction and minutes 1, 3, 5 and 10 after intubation. Method of measurement: Barometer.;Oxygen saturation percentage. Timepoint: Basic time, minutes 1 and 3 after induction and minutes 1, 3, 5 and 10 after intubation. Method of measurement: Pulse oximetry.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamidreza Shetabi

Esfahan University of Medical Sciences

hamidshetabi@med.mui.ac.ir+98 31 3668 5555

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026