Oral mucositis. Oral mucositis (ulcerative)
Conditions
Interventions
Intervention group: Patients in the intervention group are supposed to receive vitamin E mouth wash solution, that contain 400 IU of the drug in each dose, twice daily and be evaluated daily by the
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Age older than 18 years Receiving conditioning regimen with Busulfan and Cyclophosphamide
Exclusion criteria
Exclusion criteria: Showing active mucositis signs and symptoms at the time of admission Active bleeding Any contraindication to vitamin E as hypersensitivity reactions
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of oral mucositis. Timepoint: Daily for 15 days which is the duration that patient receives the formulation. Method of measurement: Clinical evaluation based on National Cancer Institute Common Terminology Criteria for Adverse Effects version 4.0 scale.;Severity of oral mucositis. Timepoint: Daily for 15 days which is the duration that patient receives the formulation. Method of measurement: Clinical evaluation based on National Cancer Institute Common Terminology Criteria for Adverse Effects version 4.0 scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of Bone Marrow Transplant ward stay. Timepoint: From the day of admission to Bone Marrow Transplant ward until discharge form the ward. Method of measurement: Medical records.;The need for narcotic analgesic. Timepoint: From the day of admission to Bone Marrow Transplant ward until discharge form the ward. Method of measurement: Medical records. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMoluk Haji Babayi
Tehran University of Medical Sciences
Outcome results
None listed