Burning Mouth Syndrome. Unspecified behavioural syndromes associated with physiological disturbances and physical factors
Conditions
Interventions
Intervention 1: Intervention group: tablet of Saffron Crocin 15 mg (prepared by a pharmacologist colleague) is prescribed twice daily. Consumption duration is determined to be 11 weeks.The severity of
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
15 Years to 65 Years
Inclusion criteria
Inclusion criteria: Daily bilateral burning sensation of oral mucosa for at least 4 to 6 months, persistent or increased burning intensity throughout the day, natural oral mucosa in clinical examination and the absence of any local or systemic causes to legitimize the irritation of the mouth, minimum burning intensity of 5 on the VAS scale for patients with BMS, not receiving any antidepressant treatment during the last 4 weeks
Exclusion criteria
Exclusion criteria: the history of systemic disease characterized by burning mouth including diabetes, severe anemia, hypothyroidism, repetitious reflux or a history of micronutrient deficiency , severe psychological disorders such as severe depression, suicide thoughts and the history of hospitalization in psychiatric hospitals, pregnant patients or ones suspected to be pregnant, reports of any susceptibility to drugs or adverse effects, the use of monoamine oxidase inhibitors, tramadol, beta-blockers, benzodiazepines, tricyclic antidepressants at present or the recent month
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Burning and pain. Timepoint: at baseline and during treatment procedure (intervals of third, seventh and eleventh week after the beginning). Method of measurement: visual analogue scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Depression and anxiety. Timepoint: 1. at baseline and during treatment procedure (intervals of the third, seventh and eleventh week after the beginning). Method of measurement: Hamilton questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactRoya zamani
Mashhad University of Medical Sciences
Outcome results
None listed