Skip to content

A comparison of the effect of Ringer Lactate versus Sodium Chloride 0.9% on maternal and neonatal acid- base state in cesarean

A comparison of the effect of Ringer Lactate versus Sodium Chloride 0.9% on maternal and neonatal acid- base state in elective cesarean delivery

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180411039267N2
Enrollment
48
Registered
2019-06-19
Start date
2019-06-01
Completion date
Unknown
Last updated
2019-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intraoperative fluid therapy, maternal and neonatal acid- base state, elective cesarean delivery.

Interventions

Intervention 1: Intervention group: In 24 pregnant women, infusion of lactate ringer serum with dose of volume therapy rule(Deficit+ Maintenance+ Loss+ Third space+ Compensated volume expansion) will

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Term parturient (pregnancy age more than 37 weeks) with physical status II ASA class candidates for elective cesarean section with spinal anesthesia Age range 18 to 45 years old In Tabriz Alzahra hospital Informed consent

Exclusion criteria

Exclusion criteria: Any contraindication of regional anesthesia Gestational hypertension, preeclampsia, eclampsia, HELLP syndrome Hypersensitivity to local anesthetics Morbid obesity Maternal co-existing disease such as a history of heart disease, pulmonary, liver and kidney disease Emergency cesarean section like fetal bradycardia, placenta previa or other conditions of peripartum hemorrhage

Design outcomes

Primary

MeasureTime frame
Maternal acid- base state during elective cesarean. Timepoint: In operating room before the spinal anesthesia and after surgery (in recovery), an arterial blood sample will be analyzed for arterial blood gases (ABG). Method of measurement: In the ABG sample, the factors PH, HCO3, Base Excess, PCO2, Po2, Hb, Hct will be analyzed and will be recorded in the checklist for this purpose.

Secondary

MeasureTime frame
Neonatal acid- base state during elective cesarean. Timepoint: Immediately after delivery and the umbilical cord closure, an umbilical artery blood sample will be sent for analysis of arterial blood gas (ABG). Method of measurement: In the ABG sample, the factors PH, HCO3, Base Excess, PCO2, Po2, Hb, Hct will be analyzed and will be recorded in the checklist for this purpose.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactReyhaneh Abri

Tabriz University of Medical Sciences

reyhane.abri@gmail.com+98 41 3553 9163

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026