infertility. Female infertility
Conditions
Interventions
Intervention 1: Intervention group: oral folate tablets 600 micrograms daily. Intervention 2: Control group: 1 mg oral folic acid tablet.
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
30 Years to 40 Years
Inclusion criteria
Inclusion criteria: Infertile women aged 30-40 with poor response or unknown causes of infertility are candidates for IVF
Exclusion criteria
Exclusion criteria: Infertility due to PCO; endometriosis; tubal and uterine and having causes of male infertility History of ovarian or pelvic surgery or medical history of chemotherapy or radiotherapy. Diseases associated with viral infections (hepatitis), tumors, autoimmune diseases, endocrine disorders, metabolic disorders or acute inflammation. Patients with definite diagnosis of hereditary diseases or family history of hereditary thrombophilic diseases in family or person. History of multivitamin use
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome: changes in the number of antral follicles. Secondary outcome: changes in FSH, AMH and Inhibin B and checking the level of possible side effects. Timepoint: The results will be evaluated at the beginning of the study and after three months from the start of the study. Method of measurement: To check AFC vaginal ultrasound and to measure FSH, AMH and Inhibin laboratory (blood sample) will be used. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMarjan Ghaemi
Tehran University of Medical Sciences
Outcome results
None listed