infertility. Female infertility
Conditions
Interventions
Intervention 1: Intervention group: Dostim protocol is performed as an intraovarian injection but with CORIFOLLITROPIN ALFA (elonva) instead of rFSH on the day of egg retrieval in the operating room,
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
32 Years to 42 Years
Inclusion criteria
Inclusion criteria: BMI<= ?? Poor responder cases with abnormal biomarkers AFC :?_??AMH <?.?-?.?) History of non-response in previous cycles (less than 3 oocytes) or first ivf experience Sperm analysis is normal or has the minimum necessary criteria for ICSI
Exclusion criteria
Exclusion criteria: History of autoimmune diseases - coagulation disorders - uterine anomalies - chromosomal and genetic disorders - chronic renal and metabolic diseases - hypo and hyperthyroidism - history of malignancy - endometriosis - history of repeated miscarriage and RIF
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The number and quality of oocytes obtained. Timepoint: On the day of puncture. Method of measurement: The number of eggs obtained on the day of puncture with OPU catheter.;Number and quality of obtained embryos. Timepoint: The day after the puncture in the embryology laboratory. Method of measurement: Under the microscope in the embryology laboratory by the embryologist. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFiroozeh Rakhshani
Tehran University of Medical Sciences
Outcome results
None listed