The effect of topical tranexamic acid on the episiotomy bleeding, a clinical trial

Clinical trial of the effect of topical tranexamic acid on the amount of episiotomy bleeding in primigravida women and comparison with the control group

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180409039247N4

Enrollment

162

Registered

2023-02-23

Start date

2023-04-05

Completion date

Unknown

Last updated

2023-03-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Episiotomy bleeding rate. Postpartum hemorrhage

Interventions

Intervention 1: Tranexamic acid mixed with 20 cc of normal saline pored in episiotomy site. Intervention 2: Control group: 20 cc of normal saline pored in episiotomy site.

Eligibility

Sex/Gender

Female

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: vagina delivery beyond 34 weeks primiparity candidates for episiotomy

Exclusion criteria

Exclusion criteria: Lack of consent to participate in the study known coagulopathy history of previous perineal surgery uterine atony retained placenta delivery with instruments Cervical rupture at the same time receiving spontaneous tranexamic acid

Design outcomes

Primary

Measure	Time frame
The primary outcomes is changes in hemoglobin and hematocrit, the need for blood transfusion, the duration of hospitalization. Timepoint: Hemoglobin and hematocrit check before admission and 12 hours later and also to check complications 1 week after discharge. Method of measurement: Hemoglobin and hematocrit check with blood test (cbc) and check the need for transfusion, discharge time, possible wound opening and thromboembolic events based on history.	—

Measure

Time frame

The primary outcomes is changes in hemoglobin and hematocrit, the need for blood transfusion, the duration of hospitalization. Timepoint: Hemoglobin and hematocrit check before admission and 12 hours later and also to check complications 1 week after discharge. Method of measurement: Hemoglobin and hematocrit check with blood test (cbc) and check the need for transfusion, discharge time, possible wound opening and thromboembolic events based on history.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Fakehi

Iran University of Medical Sciences

marjan_ghaemi@yahoo.com+98 21 5560 6034

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026