Comparison of the effect of TNG, misoprostol, dexamethasone and Foley tube along with acetaminophen on the process of dilatation and effusion in childbirth

Comparative study of the effects of TNG, misoprostol, dexamethasone and Foley catheter with acetaminophen on the process effacement and dilatation in the inactive and active phase of labor

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180409039247N3

Enrollment

240

Registered

2022-12-20

Start date

2023-01-21

Completion date

Unknown

Last updated

2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Increasing the success rate in vaginal delivery.

Interventions

Intervention 1: Intervention group: The content of the 400 micro TNG tablet is diluted with 1 cc of serum and poured into the cervix (repeat after 4 and 6 hours if Bishop does not improve). Interventi

Eligibility

Sex/Gender

Female

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Age 18-40 years old Gestational age > 37 weeks Singleton pregnancy Cephalic presentation Gravid 1

Exclusion criteria

Exclusion criteria: Cephalopelvic incompatibility Maternal medical diseases Fetal distress Uterine scar Sensitivity to studied drugs

Design outcomes

Primary

Measure	Time frame
The time interval of hospitalization for the termination of pregnancy until delivery. Timepoint: Every 6 hours. Method of measurement: Minutes.	—

Secondary

Measure	Time frame
Reducing the cesarean rate. Timepoint: At the end of the labor phase. Method of measurement: Has she had a caesarean section?.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFahimeh Ghotbizadeh

Tehran University of Medical Sciences

fghotbizadeh@yahoo.com+98 21 6119 0000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026