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Using probiotics to improve HPV infection

The effect of using probiotics on improving HPV infection in patients referred to the Gynecological Oncology Clinic ; a randomized clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180409039247N12
Enrollment
300
Registered
2025-09-08
Start date
2025-10-07
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cervical daysplasia.

Interventions

Intervention 1: Intervention group:Patients in the intervention group take probiotic medication orally once a day for 12 weeks. Intervention 2: Control group:Patients in the control group take a place

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
25 Years to 50 Years

Inclusion criteria

Inclusion criteria: Women who have a positive HPV DNA Pap smear test

Exclusion criteria

Exclusion criteria: pregnancy Patients with congenital or acquired immunodeficiency

Design outcomes

Primary

MeasureTime frame
Improvement in HPV infection after 6 months of patient follow-up. Timepoint: Checking HPV infection status through DNA testing at the beginning of the study, 6 months after the start of the study. Method of measurement: HPV testing via DNA testing.

Secondary

MeasureTime frame
Studying the prevalence of bacterial vaginosis in HPV-positive women. Timepoint: Clinical examination before and 6 months after the study. Method of measurement: Clinical examination.;The effect of probiotic consumption on improving bacterial vaginosis. Timepoint: Before and 6 months after the start of the study. Method of measurement: DNA test.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMarjan Ghaemibidgoli

Tehran University of Medical Sciences

marjan_ghaemi@yahoo.com+98 21 8800 4858

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026