Type 2 diabetes mellitus. Type 2 diabetes mellitus
Conditions
Interventions
Intervention 1: Intervention group:250 mg nitrate supplement in beetroot powder. Intervention 2: Control group: free nitrate beetroot powder( nitrate below10 mg).
Sponsors
Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: Non Pregnant and Non Breast Feeding Women
Exclusion criteria
Exclusion criteria: Women of childbearing age without using a safe Contraceptive method Smokers and alcohol consumers Consumers of hormonal medicines Consumers of antioxidant supplements Subjects with Heart, Liver, Lung, Chronic Kidney Disease and Thyroid Disorders Subjects with acute or chronic Inflammatory Diseases Phosphodiesterase 5 inhibitors, Migraine drugs (such as Sumatriptan), Allopurinol, Tri-rings Antidepressants, Antihistamines, Nitrate-containing drugs, Meperidine, and Sedative Medicines Consumers
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood glucose. Timepoint: At baseline of study, 4, 12 and 24 week. Method of measurement: Enzymatic colorimetry.;Hemoglobin glycosylated. Timepoint: At baseline of study, 4, 12 and 24 week. Method of measurement: Enzymatic method.;Triglyceride. Timepoint: At baseline of study, 4, 12 and 24 week. Method of measurement: Enzymatic colorimetry.;High density lipoprotein. Timepoint: At baseline of study, 4, 12 and 24 week. Method of measurement: Enzymatic colorimetry.;Total cholesterol. Timepoint: At baseline of study, 4, 12 and 24 week. Method of measurement: Enzymatic colorimetry. | — |
Secondary
| Measure | Time frame |
|---|---|
| Weight. Timepoint: At baseline of study, 4th,12th and 24th week. Method of measurement: Scale.;Physical activity. Timepoint: At baseline and end of study. Method of measurement: Physical activity questionnaire.;Dietary intake. Timepoint: At baseline and end of study. Method of measurement: Feed Frequency Questionnaire.;Blood pressure. Timepoint: At baseline and end of study. Method of measurement: Manometer.;Concentration of Alanine Aminotransferase. Timepoint: At baseline of study, 4th,12th and 24th week. Method of measurement: Photometry.;Aspartate aminotransferase concentration. Timepoint: At baseline of study, 4th,12th and 24th week. Method of measurement: Photometry.;Concentration of alkaline phosphatase. Timepoint: At baseline of study, 4th,12th and 24th week. Method of measurement: Photometry.;Gamma glutamyltransferase concentration. Timepoint: At baseline of study, 4th,12th and 24th week. Method of measurement: Photometry.;Thyroid Stimulating Hormon. Timepoint: At baseline of study, 4th,12th and 24th week. Method of measurement: Electrochemical Luminescence (Laboratory Kit).;Total thyroxine. Timepoint: At baseline of study, 4th,12th and 24th week. Method of measurement: Electrochemical Luminescence (Laboratory Kit).;Free thyroxine. Timepoint: At baseline of study, 4th,12th and 24th week. Method of measurement: Electrochemical Luminescence (Laboratory Kit).;Free triiodothyronine. Timepoint: at baseline of study, 4th,12th and 24th week. Method of measurement: Electrochemical Luminescence (Laboratory Kit).;Urinary microalbumin. Timepoint: At baseline of study, 4th,12th and 24th week. Method of measurement: Immunoturbidometry.;Urinary creatinine. Timepoint: At baseline of study, 4th,12th and 24th week. Method of measurement: Jaffe kinetic method.;Nitric Oxide Metabolites. Timepoint: at baseline of study, 4th,12th and 24th week. Method of measurement: Spectrophotometric method and Grease reaction.;Waist circumference. Timepoint: At baseline of study, 4th,12th and | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactZahra Bahadoran
Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences
Outcome results
None listed