Evaluation the effect of abdominal massage with Mastic gum oil on the reflux disease in children

Evaluation the effect of abdominal massage with Mastic gum oil on the symptoms of gastroesophageal reflux disease in children 2month-1year compared to abdominal massage without oil.

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180406039204N1

Enrollment

Registered

2018-05-16

Start date

2018-05-10

Completion date

Unknown

Last updated

2018-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastroesophageal reflux. Gastro-esophageal reflux disease

Interventions

Intervention 1: Intervention group:Omeprazole capsule and abdominal massage with mastic gum oil.Omeprazole (Abidi®) will be prescribed 1 mg/kg/day in1 Dose,Fasting morning before child feeding .Abdo

Eligibility

Sex/Gender

All

Age

2 Months to 1 Years

Inclusion criteria

Inclusion criteria: Children more than two months and less than 1 years old in aliasghar hospital Diagnosis of GERD on the basis of GSQ-I questionnaire and pediatric gastroenterologist Absence of serious gastrointestinal diseases such as esophagitis, achalasia, gastrointestinal ulcers, IBD (Inflamatory Bowel disease),….

Exclusion criteria

Exclusion criteria: History of allergy or skin allergy to the drug or herbal compounds Allergy to cow's milk protein Infants with a history of gastrointestinal surgery and neurological disease, liver, kidney, or history of severe cardio-pulmonary disease, as well as history of peptic ulcer Guardian to cooperate in filling the forms (cognitive or language disorder).

Design outcomes

Primary

Measure	Time frame
Severity of css index. Timepoint: At the beginning of the study, 14 days after the intervention and 7? 28 days after discontinuation of treatment. Method of measurement: GSQ-I questionnaire.;Severity and frequency of vomiting. Timepoint: At the beginning of the study, 14 days after the intervention and 7? 28 days after discontinuation of treatment. Method of measurement: GSQ-I questionnaire.;Severity and frequency of crying and restlessness while breastfeeding. Timepoint: At the beginning of the study, 14 days after the intervention and 7? 28 days after discontinuation of treatment. Method of measurement: GSQ-I questionnaire.	—

Measure

Time frame

Severity of css index. Timepoint: At the beginning of the study, 14 days after the intervention and 7? 28 days after discontinuation of treatment. Method of measurement: GSQ-I questionnaire.;Severity and frequency of vomiting. Timepoint: At the beginning of the study, 14 days after the intervention and 7? 28 days after discontinuation of treatment. Method of measurement: GSQ-I questionnaire.;Severity and frequency of crying and restlessness while breastfeeding. Timepoint: At the beginning of the study, 14 days after the intervention and 7? 28 days after discontinuation of treatment. Method of measurement: GSQ-I questionnaire.

—

Secondary

Measure	Time frame
Side efect. Timepoint: Any time during the study. Method of measurement: Report by the child's supervisor.;Time Control Signs. Timepoint: Any time during the study. Method of measurement: Report by the child's supervisor.;Recurrence of symptoms. Timepoint: 7 and 28 days after discontinuation of treatment. Method of measurement: Report by the child's supervisor.	—

Countries

Iran (Islamic Republic of)

Contacts

Public Contactmansooreh akhavan

Iran University of Medical Sciences

stm@iums.ac.ir+98 21 5558 0388

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026