Peri-trochanteric fractures. Pertrochanteric fracture
Conditions
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Admission to the orthopedic department of Talaghani Hospital with a diagnosis of pertrochanteric fractures. Age between 18 and 60 years. Injury Severity Score (ISS) less than 15. Willingness to cooperate and sign an informed consent form after full awareness of the study objectives and methods by the patient or their legal guardian.
Exclusion criteria
Exclusion criteria: Pregnancy and lactation. Septic patients with unstable hemodynamics and metabolism. History of autoimmune diseases or disorders. History of cancer. Chemotherapy and radiotherapy within the past month. Diabetes mellitus Any type of liver failure Human immunodeficiency virus (HIV) infection. Morbid obesity (BMI > 40) Unwillingness to participate in the study Significant change in the patient's treatment process or admission to the ICU Intolerance to trehalose Patient being NPO and unable to start oral feeding Development of infection during the recovery and improvement period Alcohol consumption Smoking Different and heavy physical activity programs Those who are on a specific diet throughout the study Weight changes (±3) during the study Have a history of taking antibiotics and non-steroidal anti-inflammatory drugs (NSAIDs) during the last month
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of wound healing. Timepoint: At the beginning of the study, measurements are taken on the second day, in week 2 and week 4. Method of measurement: Wound healing index.;IL-6. Timepoint: At the beginning of the study, week 4 and week 12 measurements will be taken. Method of measurement: Measurement of serum levels of IL-6. | — |
Secondary
| Measure | Time frame |
|---|---|
| ESR. Timepoint: at the beginning of study, week 4, week 12. Method of measurement: Measurement of serum levels of ESR.;CRP. Timepoint: at the beginning of the study, week 4, week 12. Method of measurement: Measurement of serum levels of CRP.;TNF-a. Timepoint: at the beginning of the study, week 4, week 12. Method of measurement: Measurement of serum levels of TNF-a.;CBC. Timepoint: at the beginnig of the study, week 4, week 12. Method of measurement: Blood test. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactReza Zandi
Shahid Beheshti University of Medical Sciences
Outcome results
None listed