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evaluation effect of Pentoxifylline in sepsis.

The study of efficacy of Pentoxifylline in late Sepsis in preterm neonate(Trial clinical randomized)

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180404039187N7
Enrollment
40
Registered
2020-06-22
Start date
2020-04-20
Completion date
Unknown
Last updated
2020-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

neonatal late sepsis. Other sepsis

Interventions

Intervention 1: Intervention group: received Pentoxyfilin orally at a dose of 10 mg/kg every eight hours for 6 day with routin antibiotic treatment(Amikacin at a dose of 15-20 mg\kg-Vankomycin at a do

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 259 Days

Inclusion criteria

Inclusion criteria: Preterm neonate with positive blood culture of sepsis clinical signs of sepsis: temprature instability respiratory disorders cardiovascular disorders gastrointestinal disorders preterm neonates with late onset sepsis(having sepsis 72 hours after birth)

Exclusion criteria

Exclusion criteria: neonate with cranial hemorrhage maternal infection renal disorders neonate with tolerance to xanthine products that cause anaphylactic reaction

Design outcomes

Primary

MeasureTime frame
Number of hospitalized days. Timepoint: During the study. Method of measurement: Count the days of hospitalization.;Duration of making CRP marker negative. Timepoint: At the beginning and during the study. Method of measurement: laboratory tests.;Need for intubation and mechanical ventilarion. Timepoint: During the study. Method of measurement: Checking patient records.;Metabolic acidosis. Timepoint: During the study. Method of measurement: Laboratory test(ABG).;Duration needed for oxygene therapy. Timepoint: During the study. Method of measurement: Counting days under oxygen therapy.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactTabriz University of Medical Sciences

Tabriz University of Medical Sciences

Elnaz_shaseb_64@yahoo.com0098 144933344198

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026