Hemodialyzied kidney desease patients. Chronic kidney disease, stage 5
Conditions
Interventions
Intervention 1: Intervention group: 40 mg curcumin three times a day for 12 weeks. Intervention 2: Control group: placebo three times a day for 12 weeks.
Sponsors
Islamic Azad University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Having a history of at least 6 months of dialysis Hemodialysis 2-3 times a week for 4 hours
Exclusion criteria
Exclusion criteria: Patients with infectious diseases such as hepatitis Patients with chronic inflammatory diseases, including rheumatoid arthritis and lupus Use of steroidal and non-steroidal anti-inflammatory drugs Receive omega-3 fatty acids and carnitine at least 1 month before the start of the study Liver disease and thyroid disorders Planning for kidney transplantation during the study No Patient's tendency to stay in study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TNF-a. Timepoint: At the beginning of the study and after 12 weeks of intervention. Method of measurement: Real-Time PCR.;IL6. Timepoint: At the beginning of the study and after 12 weeks of intervention. Method of measurement: Real-Time PCR.;ICAM-1. Timepoint: At the beginning of the study and after 12 weeks of intervention. Method of measurement: Blood test.;VCAM-1. Timepoint: At the beginning of the study and after 12 weeks of intervention. Method of measurement: Blood test. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactYousef Rasmi
Oroumia University of Medical Sciences
Outcome results
None listed