The effect of letrozole and dexamethasone on ovarian response

Comparison the effect of letrozole and dexamethasone with letrozole alone on ovarian response in infertile women

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180318039129N1

Enrollment

120

Registered

2018-03-27

Start date

2018-04-04

Completion date

Unknown

Last updated

2018-04-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility. Female infertility

Interventions

Intervention 1: Intervention group 1: Letrozole 10 mg form the days 3-5 of the cycle for 5 days plus 0.5 mg oral dexamethasone from the day 4 to 15 of the cycle. Intervention 2: Intervention group 2:

Eligibility

Sex/Gender

Female

Age

18 Years to 39 Years

Inclusion criteria

Inclusion criteria: All infertile women with polycystic ovarian syndrome Age 18-39 years

Exclusion criteria

Exclusion criteria: Using corticosteroid drugs History of surgery on ovaries Endocrine abnormalities such as thyroid gland disorders

Design outcomes

Primary

Measure	Time frame
Follicle diameter. Timepoint: Between the days 12-14 of the cycle. Method of measurement: By trans-vaginal ultrasonography.;Endometrial thickness. Timepoint: Between the days 12-14 of the cycle. Method of measurement: By trans-vaginal ultrasonography.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Afshar

Zahedan University of Medical Sciences

dr.f.afshar@zaums.ac.ir+98 54 3329 5715

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026