Comparison of the Effects of Two Treatment Methods on Managing Refractory Reflux

Comparing the effectiveness of acupuncture versus medication in managing gastric reflux in treatment-resistant patients.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180313039085N5

Enrollment

Registered

2025-05-12

Start date

2026-04-21

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastroesophageal reflux disease. Gastro-esophageal reflux disease

Interventions

Intervention 1: Intervention group: Omeprazole 20 mg twice daily. Intervention 2: Intervention group: Traditional Chinese acupuncture twice a week.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: All patients suffering from reflux whose condition has persisted for more than two months Experiencing reflux at least twice a week.

Exclusion criteria

Exclusion criteria: Underlying medical conditions Pregnancy Breastfeeding Drug-induced esophagitis Drug abuse Use of psychotropic drugs Use of antidepressants Chemotherapy Radiotherapy

Design outcomes

Primary

Measure	Time frame
Heartburn. Timepoint: At study entry and 4 weeks later. Method of measurement: Gastro-oesophageal reflux disease questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNeda Gorjizadeh

Tehran University of Medical Sciences

gorjizadehn@yahoo.com+98 21 6634 8500

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026