Liver cirrhosis. Cirrhosis of the liver
Conditions
Interventions
Intervention 1: Intervention group 1: 1000 mg L Carnitine by Zist Takhmir company will use daily for 24 weeks. Intervention 2: Intervention group 2: 2000 mg L Carnitine by Zist Takhmir company will
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Cirrhotic patients who referred to Liver clinic of Taleghani hospital with age 18-70 years old Cirrhotic patients who referred to Liver clinic of Taleghani hospital with known case of cirrhosis Cirrhotic patients who referred to Liver clinic of Taleghani hospital with Child score A or B Cirrhotic patients who referred to Liver clinic of Taleghani hospital with no administration of L-Carnitine before
Exclusion criteria
Exclusion criteria: Not tolerate use of L-Carnitine because of the gastrointestinal problem Gastrointestinal bleeding Uncontrolled malignant tumors Need of hemodialysis Pregnancy Receiving drugs causing hyperammonemia Overt hepatic encephalopathy Patients who do not accept to continue the study Patients with other significant background diseases (heart failure, chronic kidney disease,…)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of life. Timepoint: First, 3 months later, 6 months later. Method of measurement: Standard questionnaire for quality life in cirrhotic patients.;Sarcopenia. Timepoint: First, 3 months later, 6 months later. Method of measurement: Evaluate gripe strength by dynamometer and muscle mass by bioelectrical impedance analysis (BIA). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactLeila Pasharavesh
Shahid Beheshti University of Medical Sciences
Outcome results
None listed