Comparison of Surgical and non-surgical therapies in Infants with ureteropelvic junction obstruction

Results of early pyeloplasty and maintenance therapy in asymptomatic infants with grade III and IV ureteropelvic junction obstruction(UPJO)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180310039030N1

Enrollment

Registered

2019-02-19

Start date

2018-04-21

Completion date

Unknown

Last updated

2019-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ureteropelvic Junction Obstruction. Hydronephrosis with ureteropelvic junction obstruction

Interventions

Intervention 1: Intervention group: asymptomatic patient under age of one year with ureteropelvic junction obstruction undergoing dismembered reduction pyeloplasty. Intervention 2: Control group: asym

Eligibility

Sex/Gender

All

Age

1 Months to 1 Years

Inclusion criteria

Inclusion criteria: All asymptomatic children under one year of age with ureteropelvic junction obstruction (UPJO) (grade 3 or 4 hydronephroses) The kidney differential function (DRF) is based on the results of isotope scans at least 40% or higher.

Exclusion criteria

Exclusion criteria: All children under one year of age with ureteropelvic junction obstruction( UPJO ) with symptoms such as urinary tract infections, palpable kidney pain The presence of ureteral and kidney anomalies Ultrasonography represents structural anomalies voiding cystourethrogram (VCUG) represents urinary reflux and posterior urethral valve (PUV)

Design outcomes

Primary

Measure	Time frame
The degree of Ureteropelvic Junction Obstruction. Timepoint: before intervention 1 week later 3 and 6 months later to one year. Method of measurement: Ultra sonography ,radioisotope scan.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactKhashayar Atqiaee

Shahid Beheshti University of Medical Sciences

khashayar_atqiaee@sbmu.ac.ir+98 21 2222 7021

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026