Effect of synbiotic in diabetes

The effect of synbiotic supplementation on glycemic factor, lipid profile, Total antioxidant capacity and serum inflammatory factors in patients with type 1 diabetes.

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180310039020N1

Enrollment

Registered

2018-05-11

Start date

2018-06-22

Completion date

Unknown

Last updated

2018-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

type1 Diabetes. Type 1 diabetes mellitus

Interventions

Intervention 1: Intervention group: The intervention group consumes 1 g of synbiotic supplement with a glass of water once a day after lunch for 8 weeks. Intervention 2: Control group: In the control

Eligibility

Sex/Gender

All

Age

4 Years to 18 Years

Inclusion criteria

Inclusion criteria: All of type 1 diabetes who have at least 1 year of diagnosis ?According to BMI for age chart, their body mass index is below 95%

Exclusion criteria

Exclusion criteria: Unwillingness of patients to participate in the study Renal diseases, coronary arteries, acute and chronic inflammation of the lungs, short stomach cyst syndrome, allergies, pregnancy, lactation Traveling for more than 2 weeks Smokers, the use of food supplements, anti-inflammatory drugs, the use of any antioxidant supplements in the last 3 months, the use of immunosuppressive drugs Follow certain diets, change your diet or decide to lose weight

Design outcomes

Primary

Measure	Time frame
Blood sugar in the morning. Timepoint: Before and after the intervention. Method of measurement: Use of the kit in an enzymatic method.;HbA1C. Timepoint: Before and after the intervention. Method of measurement: Use of the kit in an enzymatic method.;LDL cholesterol. Timepoint: Before and after the intervention. Method of measurement: Use of the kit in an enzymatic method.;HDL cholesterol. Timepoint: Before and after the intervention. Method of measurement: Use of the kit in an enzymatic method.;Tri glyceride. Timepoint: Before and after the intervention. Method of measurement: Use of the kit in an enzymatic method.;Total cholesterol. Timepoint: Before and after the intervention. Method of measurement: Use of the kit in an enzymatic method.;TNF-a. Timepoint: Before and after the intervention. Method of measurement: Eliza.;Hs-CRP. Timepoint: Before and after the intervention. Method of measurement: Eliza.;TAC. Timepoint: Before and after the intervention. Method of measurement: Eliza.;Insulin serum. Timepoint: Before and after the intervention. Method of measurement: Elisa.;Insulin resistance (HOMA-IR). Timepoint: Before and after the intervention. Method of measurement: Elisa.;IL-6. Timepoint: Before and after the intervention. Method of measurement: Elisa.	—

Measure

Time frame

Blood sugar in the morning. Timepoint: Before and after the intervention. Method of measurement: Use of the kit in an enzymatic method.;HbA1C. Timepoint: Before and after the intervention. Method of measurement: Use of the kit in an enzymatic method.;LDL cholesterol. Timepoint: Before and after the intervention. Method of measurement: Use of the kit in an enzymatic method.;HDL cholesterol. Timepoint: Before and after the intervention. Method of measurement: Use of the kit in an enzymatic method.;Tri glyceride. Timepoint: Before and after the intervention. Method of measurement: Use of the kit in an enzymatic method.;Total cholesterol. Timepoint: Before and after the intervention. Method of measurement: Use of the kit in an enzymatic method.;TNF-a. Timepoint: Before and after the intervention. Method of measurement: Eliza.;Hs-CRP. Timepoint: Before and after the intervention. Method of measurement: Eliza.;TAC. Timepoint: Before and after the intervention. Method of measurement: Eliza.;Insulin serum. Timepoint: Before and after the intervention. Method of measurement: Elisa.;Insulin resistance (HOMA-IR). Timepoint: Before and after the intervention. Method of measurement: Elisa.;IL-6. Timepoint: Before and after the intervention. Method of measurement: Elisa.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMona jamalvandi

Ahvaz University of Medical Sciences

jamalvandi.m@ajums.ac.ir+98 61 3333 3477

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026