Study of the Effect of bread containing flaxseed on serum level of Apelin and lipid profile in hyperlipidemic patients

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180305038966N1

Enrollment

Registered

2018-03-29

Start date

2018-01-28

Completion date

Unknown

Last updated

2018-04-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hyperlipidemia. Disorders of lipoprotein metabolism and other lipidemias

Interventions

Intervention 1: Intervention group: intake 2 unit of bread containing 20 gram of flax seed flour and 80 gram of wheat flour for 6 weeks and twice a day. Intervention 2: Control group: intake 2 unit o

Eligibility

Sex/Gender

All

Age

20 Years to 50 Years

Inclusion criteria

Inclusion criteria: high is one of the lipid factors: cholesterol is grater than or equal to 200.triglycerides grater or equal. LDL is grater or equal 130 and rate of HDL is less than 40 for men and 50 mg per deciliter for women(high levels of LDL or cholesterol are essential Men and wemen 20-50 years old Patients who agree to participate in the study

Exclusion criteria

Exclusion criteria: Tobacco use Adherence to a particular diet Consumption bread of flaxseed in the last 6 months Pregnancy, breast feeding, menopause

Design outcomes

Primary

Measure	Time frame
Serum level of LDL. Timepoint: At the beginning of the study and the end of the sixth week. Method of measurement: By enzyme _ mg/dl.;Serum level of total cholesterol. Timepoint: At the beginning of the study and the end of the sixth week. Method of measurement: By enzyme _ mg/dl.;Serum level of Apelin. Timepoint: At the beginning of the study and the end of the sixth week. Method of measurement: Eliza_ picogram/ml.;Serum level of triglyceride. Timepoint: At the beginning of the study and the end of the sixth week. Method of measurement: By enzyme _ mg/dl.;Serum level of HDL. Timepoint: At the beginning of the study and the end of the sixth week. Method of measurement: By enzyme _ mg/dl.;Blood pressure. Timepoint: At the beginning of the study and the end of the sixth week. Method of measurement: Digital Manometer mmHg.;Body mass index. Timepoint: At the beginning of the study and the end of the sixth week. Method of measurement: Formula weight/High2.;Physical activity. Timepoint: Initially, the middle and end of the sixth week study. Method of measurement: Met questionnaire.;Food intake. Timepoint: Initially, the middle and end of the sixth week study. Method of measurement: Food frequency questionnaire 3 days.;Waist. Timepoint: At the beginning of the study and the end of the sixth week. Method of measurement: Strip Meter- centimeters.	—

Measure

Time frame

Serum level of LDL. Timepoint: At the beginning of the study and the end of the sixth week. Method of measurement: By enzyme _ mg/dl.;Serum level of total cholesterol. Timepoint: At the beginning of the study and the end of the sixth week. Method of measurement: By enzyme _ mg/dl.;Serum level of Apelin. Timepoint: At the beginning of the study and the end of the sixth week. Method of measurement: Eliza_ picogram/ml.;Serum level of triglyceride. Timepoint: At the beginning of the study and the end of the sixth week. Method of measurement: By enzyme _ mg/dl.;Serum level of HDL. Timepoint: At the beginning of the study and the end of the sixth week. Method of measurement: By enzyme _ mg/dl.;Blood pressure. Timepoint: At the beginning of the study and the end of the sixth week. Method of measurement: Digital Manometer mmHg.;Body mass index. Timepoint: At the beginning of the study and the end of the sixth week. Method of measurement: Formula weight/High2.;Physical activity. Timepoint: Initially, the middle and end of the sixth week study. Method of measurement: Met questionnaire.;Food intake. Timepoint: Initially, the middle and end of the sixth week study. Method of measurement: Food frequency questionnaire 3 days.;Waist. Timepoint: At the beginning of the study and the end of the sixth week. Method of measurement: Strip Meter- centimeters.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactNahid Shakeri

Islamic Azad University

nutrition@mail.mui.ac.ir+98 21 4486 1815

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026