COVID19. Coronavirus infection, unspecified
Conditions
Interventions
Intervention 1: Intervention group: all the patients are required to fill the consent form to be able to enter the trial. 50 patients admitted in the COVID ward with definitive moderate COVID19 diagno
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Both genders Age ranging from18 to 80 Y.O. who are admitted in hospital showing at least one of these criteria: Fever (Oral temperature = 38 ?) , Respiratory rate >24/min , O2Sat<93% in room air or the Pa02/Fi02 ratio =300mgHg Laboratory (RT-PCR) confirming the infection with 2019-Covid Virus Lung involvement in CT-Scan less than 50 % ( in compliance with the involvement of moderate COVID19 ) 5 =days since onset of the COVID19 symptoms =10
Exclusion criteria
Exclusion criteria: History of allergic reaction to the drugs used in this clinical trial in a pregnancy or breast feeding status test Receipt of any experimental treatment for COVID-19 before hand Heart rate < 60/min currently on amiodarone prescription presence of multi organ failure evidence in need of mechanical ventilation estimated glomerular filtration rate < 50 0mL/1.73 m2/min admitted in ICU ward who are in shock
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to reach clinical recovery. Timepoint: after 10 days on treatment initiation. Method of measurement: daily physical exam, assessing vanishing of tachypnea ,blood saturation of O2(using pulse-oximeter) , fever( using thermometer). | — |
Secondary
| Measure | Time frame |
|---|---|
| The rate of patients who need to admit in ICU ward. Timepoint: 14 days after Treatment initiation. Method of measurement: physical exam and paraclinical evaluation.;The rate of patient expiry in each arm. Timepoint: 14 days after treatment initiation. Method of measurement: questionnaire.;Remission of clinical symptoms in each arm. Timepoint: 14 days after treatment initiation. Method of measurement: physical exam ( thermometer and pulse-oximeter). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFariba Ghorbani
Shahid Beheshti University of Medical Sciences
Outcome results
None listed