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The Effect of Levothyroxine on Cardiac Function in Children with Subclinical Hypothyroidism

The Effect of Levothyroxine on Cardiac Function in Children with Subclinical Hypothyroidism

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180228038900N3
Enrollment
30
Registered
2018-12-02
Start date
2018-10-14
Completion date
Unknown
Last updated
2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypothyroidism Subclinical. Iodine-deficiency-related (endemic) goitre, unspecified

Interventions

Intervention group: For patients, 0.1 mg levothyroxine tablets are prescribed by Iranian company Hormones with a dose of 4 micro/miligrams per day..

Sponsors

Babol University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
4 Years to 12 Years

Inclusion criteria

Inclusion criteria: Diagnosis of subclinical hypothyroidism

Exclusion criteria

Exclusion criteria: Obese children Children with hypertension Children who already use levothyroxine Children with congenital or acquired heart disease proven and under medical treatment Children with liver or kidney disease Children with high blood lipids Children with diabetes Children with infectious diseases

Design outcomes

Primary

MeasureTime frame
Left ventricular end-systolic diameter. Timepoint: Before starting treatment. Method of measurement: Echocardiography.;Left ventricular end-Dystolic diameter. Timepoint: Before starting treatment. Method of measurement: Echocardiography.;Fractional - Shortening. Timepoint: Before starting treatment. Method of measurement: Echocardiography.;Tissue Doppler echocardiography. Timepoint: Before starting treatment. Method of measurement: Echocardiography.;Ejection fraction. Timepoint: Before starting treatment. Method of measurement: Echocardiography.;Myocardial Perfusion Imaging. Timepoint: Before starting treatment. Method of measurement: Echocardiography.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMorteza Alihanpour Aghamaleki

Babol University of Medical Sciences

m.alijanpour@mubabol.ac.ir+98 11 3234 6963

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026