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Effect of Synbiotics on Neonatal hyperbilirubinemia

Therapeutic effects of Synbiotics plus phototherapy on decreasing bilirubin level in 3-14 day old icteric Neonates with gestational age >35 weeks and comparison with only phototherapy theraputic effect

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180228038895N1
Enrollment
194
Registered
2018-09-26
Start date
2018-10-12
Completion date
Unknown
Last updated
2018-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

neonatal hyperbilirubinemia and symbiotic effect on its treatment.

Interventions

Intervention 1: Intervention group will receive 5 drops of oral Pedilact before breast feeding, once a day, until the day of discharge in addition to routine phototherapy,. Pedilact is a Synbiotic an

Sponsors

Rasht University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Days to 14 Days

Inclusion criteria

Inclusion criteria: Age between 3-14 days Total bilirubin between 15-22 mg/dl and direct bill 2500gr

Exclusion criteria

Exclusion criteria: Sepsis Cephalhematoma ABO incompatibility G6PD deficiency Underlying disease Parental dissatisfaction Polycythemia RH incompatibility Formula feeding Treated by Phenobarbital .billinaster.etc... Transfer to NICU Down Syndrome Family history of Immune deficiency Blood exchange Treated by Antibiotics Serum therapy Hemolysis Diabetes in Mother

Design outcomes

Secondary

MeasureTime frame
Daily defecation numbers. Timepoint: Daily at 8 AM until discharge. Method of measurement: Question from parents.

Primary

MeasureTime frame
Bilirubin level. Timepoint: Measurement of Bilirubin in admission day and daily until discharge(8 AM). Method of measurement: Measurement of serum bilirubin in laboratory by Pars Azmoon kits.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyedeh Azadeh Hosseini Nouri

Rasht University of Medical Sciences

dr.azadehoseini@gums.ac.ir+98 13 3336 9026

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026