The Effect of Synbiotic on Lymphedema

The Effect of Synbiotic Supplementation on Quality of Life and Volume of Lymphedema in Breast Cancer Survivors with Lymphedema

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180226038874N1

Enrollment

132

Registered

2018-04-15

Start date

2018-04-21

Completion date

Unknown

Last updated

2018-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lymphedema. Malignant neoplasm of breast of unspecified site

Interventions

Intervention 1: Intervention group: weight loss diet consultation (At the beginning of the study all the participants, according to their age, height, weight and calculating Energy Expenditure, should

Eligibility

Sex/Gender

Female

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Women with unilateral Breast Cancer related Lymphedema Breast Cancer Lymphedema in Stage 2 Age Range Between 18 to 60 years BMI Between 25 to 35 Kg/m2 At least one Month has Passed Since the last Treatment Such as Radiotherapy Willingness to Participate in the Study

Exclusion criteria

Exclusion criteria: Use of Multivitamin Minerals and Omega 3 Supplements up to 1 Month Before the Study Began Inflammatory Diseases Such as Heart Failure, Pulmonary, Kidney and Diabetes Autoimmune Diseases Such as Rheumatoid Arthritis Acute and Chronic Infection Taking Probiotics Supplementation from 6 Months Before Study Having a Weight Loss Diet in Length 6 Months Before the Study Smoking and Alcohol Consumption Lymphedema due to other Cancers

Design outcomes

Primary

Measure	Time frame
Quality of Life. Timepoint: Before and after the intervention. Method of measurement: Questionnaire.	—

Secondary

Measure	Time frame
Volume of lymphedema. Timepoint: Before and after the intervention. Method of measurement: Water tank technique.;BMI. Timepoint: Before and after the intervention. Method of measurement: calculate.;Skin fold thickness. Timepoint: Before and after the intervention. Method of measurement: Caliper.;Waist. Timepoint: Before and after the intervention. Method of measurement: Meter.;Nutrition status. Timepoint: Before and after the intervention. Method of measurement: Measurement of energy and nutrients intake using a 24 hour dietary recall questionnaire and anthropometric indices using scales and measurements.;Physical activity. Timepoint: Before and after the intervention. Method of measurement: IPAQ questionnaire.	—

Measure

Time frame

Volume of lymphedema. Timepoint: Before and after the intervention. Method of measurement: Water tank technique.;BMI. Timepoint: Before and after the intervention. Method of measurement: calculate.;Skin fold thickness. Timepoint: Before and after the intervention. Method of measurement: Caliper.;Waist. Timepoint: Before and after the intervention. Method of measurement: Meter.;Nutrition status. Timepoint: Before and after the intervention. Method of measurement: Measurement of energy and nutrients intake using a 24 hour dietary recall questionnaire and anthropometric indices using scales and measurements.;Physical activity. Timepoint: Before and after the intervention. Method of measurement: IPAQ questionnaire.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Shahpar Haghighat

Iranian academic center for education culture and research

sh_haghighat@yahoo.com+98 21 8879 1120

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026