Intranasal naloxone for treatment of opioid poisoning in children

Intranasal versus Intravenous Naloxone in opium poisoning in children.

Status

Recruiting

Phases

Phase 1

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180226038869N1

Enrollment

Registered

2019-02-22

Start date

2018-03-21

Completion date

Unknown

Last updated

2019-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pediatrics Poisoning.

Interventions

Intervention 1: Intervention group: Dribbling of intra nasal Naloxone 0.01mg/kg. Intervention 2: Control group: Intravenous injection of Naloxone 0.01mg/kg.

Eligibility

Sex/Gender

All

Age

1 Years to 13 Years

Inclusion criteria

Inclusion criteria: Opium poisoning 1-13 years No nasal congestion Parental agreement

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Respiratory Rate in one minute and register in questionnaire . Timepoint: Before and after intervention every minute till clinical response. Method of measurement: Physician Observation.;Level of conscious. Timepoint: Before and after intervention every minute till recovery. Method of measurement: Physician Observation with Glascow coma scale.;O2 Saturation. Timepoint: Before and after intervention every minute till recovery. Method of measurement: Pulse oximetery.	—

Measure

Time frame

Respiratory Rate in one minute and register in questionnaire . Timepoint: Before and after intervention every minute till clinical response. Method of measurement: Physician Observation.;Level of conscious. Timepoint: Before and after intervention every minute till recovery. Method of measurement: Physician Observation with Glascow coma scale.;O2 Saturation. Timepoint: Before and after intervention every minute till recovery. Method of measurement: Pulse oximetery.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFariba Farnaghi

Shahid Beheshti University of Medical Sciences

faribafarnaghi@yahoo.com+98 21 5102 5000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 19, 2026