efficacy of laser therapy on Recurrence Wound healing of herpes simplex virus 1 infection

effect of low-level laser therapy on Recurrence Wound healing of herpes simplex virus 1 infection

Status

Recruiting

Phases

Phase 1

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180224038840N2

Enrollment

Registered

2021-10-18

Start date

2021-09-23

Completion date

Unknown

Last updated

2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Wounds Caused by Recurrence of Herpes Simplex Virus Type 1 Infection. Herpesviral vesicular dermatitis

Interventions

Intervention 1: Intervention group: this group received acyclovir ointment 5 times a day for 5 days and diode laser irradiation in one session for the first 24 to 48 hours after the lesion. Intervent

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Signs and symptoms of herpes labialis virus infection

Exclusion criteria

Exclusion criteria: Definitive diagnosis of herpes by taking a history by an oral health specialist Onset of herpes lesions more than 48 hours

Design outcomes

Primary

Measure	Time frame
Pain intensity. Timepoint: The pain intensity was evaluated after treatment at1 and 3 days follow-up sessions. Method of measurement: visual analogue scale (VAS).;Lesion size. Timepoint: Recurrence Wound healing was evaluated 1, 3, 7 days before and 10 after treatment by measuring the lesion size (mm). Method of measurement: According to lesion size , 0 represented lack of lesion, 0-2 mm represented mild lesions , 2-5 mm represented moderate lesions , 5 mm< represented large lesions.;Time to healing. Timepoint: followed 10 days after treatment. Method of measurement: day.	—

Measure

Time frame

Pain intensity. Timepoint: The pain intensity was evaluated after treatment at1 and 3 days follow-up sessions. Method of measurement: visual analogue scale (VAS).;Lesion size. Timepoint: Recurrence Wound healing was evaluated 1, 3, 7 days before and 10 after treatment by measuring the lesion size (mm). Method of measurement: According to lesion size , 0 represented lack of lesion, 0-2 mm represented mild lesions , 2-5 mm represented moderate lesions , 5 mm< represented large lesions.;Time to healing. Timepoint: followed 10 days after treatment. Method of measurement: day.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Seyed Amir Seyed

Oroumia University of Medical Sciences

Seyedi.a@umsu.ac.ir+98 44 3223 4897

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026