Condition 1: Migraine without aura(common migraine). Condition 2: Migraine with aura ( classic migraine ). Migraine without aura Migraine with aura
Conditions
Interventions
Intervention 1: Intervention group: Sodiom Valproate (Depakine), manufactured by Sanofi S.P.A./Italy , 1200 mg in 250 cc Normal Salin , administerd intravenously over 15 minutes for the patie
Sponsors
Ahvaz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 58 Years
Inclusion criteria
Inclusion criteria: The chief complaint of patients is acute headache. Positive past history of Migraine headache Intensity of headache equal or more than four base on VAS score Age equal or more than 18 to less or equal than 58 years old. Body weight equal or more than 50 to less or equal than 80 kg.
Exclusion criteria
Exclusion criteria: BP more than 160/100 mmHg SBP less than 100 mmHg PR less than 50 /Min Pregnancy or lactation Presens of systemic disease( Cardiovascular ,Pulmonary ,Metabolic ,Liver &Renal insufficiency ,Cancer ,Seizure ) Use of Anticoagolant & Anticonvulsant & Antimetobolit drugs. Use of any IV sedative drugs in 4 h. ago. Use of Ergot &Triptamin component recently to 24 h. Positive history of hypersensitivity to Dexamethazon & Sodiom Valproate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Decrease of Migrainuos Headache severity and related symptoms,. Timepoint: 0.5 , 1 , 2 hour after use of medication,. Method of measurement: VAS score. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohammad Reza Dadkhah Tehrani
Ahvaz University of Medical Sciences
Outcome results
None listed