The effect of N_Acettyl cysteine on hepatectomy outcome

The comparison of effect of Mannitol infusion and N Acettyl Cysteine on liver function in patients undergoing partial hepathectomy

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180221038809N1

Enrollment

Registered

2018-05-15

Start date

2018-03-11

Completion date

Unknown

Last updated

2018-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatic mass

Interventions

N acettyl cystein is an amino acid with a sulfur base and thiol. Drug is in form of 2gr/ ml vials and was injected by dose of 100mg/kg before hepatic artery clamping intraoperatively to group 1 patein

Eligibility

Sex/Gender

All

Age

15 Years to 60 Years

Inclusion criteria

Inclusion criteria: age ASA class1 & ASA class 2 No mortal clinical illness

Exclusion criteria

Exclusion criteria: ASA class 3 & ASA class 4 Sever coagulopathy ESRD Cirrhosis

Design outcomes

Primary

Measure	Time frame
Liver enzeymes; Coagulation profile; Acid-Base profile. Timepoint: Lab data during operation, 6,12,24 hrs and 3 days after surgery. Method of measurement: IU/L for liver enzymes, (Mg/dl for PT, PTT, INR), PH For asidosis.	—

Secondary

Measure	Time frame
Bun and Cr was checked. Timepoint: Bun & Cr data were checked 6? 12 and 24 hrs after surgery. Method of measurement: Blood sampling.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMasoomeh Alizadeh

Ahvaz University of Medical Sciences

dr.alizadeh.92@google.com+98 61 3373 8383

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026