Poor ovarian responds patients. Ovarian dysfunction
Conditions
Interventions
Intervention 1: This study is a prospective randomized clinical trial. Patients who are nominated for ICSI because of POR are divided into two groups of 30 individuals randomly. After completing the c
Sponsors
Iranian academic center for education culture and research
Eligibility
Sex/Gender
Female
Age
40 Years to 45 Years
Inclusion criteria
Inclusion criteria: Age over 40. History of getting less than four oocyte retival in previous cycle Abnormal ovarian reserve tests. History of previous ovarian surgery or history of chemotherapy Different risk factors involved in ovarian response weakness
Exclusion criteria
Exclusion criteria: BMI value is equal to 35 and higher FSH more than 25 Grade 3 endometriosis and higher Any contraindication for ovarian stimulation such as uncontrolled systemic diseases Sever male infertility based on WHO indexes
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1-The number of retrieved oocytes. Timepoint: Measuring the number of follicles in the first menstrual cycle and after taking ovulation-inducing drugs. Method of measurement: Ultrasouand system.;The number and quality of the obtained embryos. Timepoint: In follicular and luteal phase. Method of measurement: Ultrasouand system.;Measurement of serum Progesterone. Timepoint: On the day the gonadotropins started, and on the day of the trigger with Deca in the follicular and luteal phase. Method of measurement: ELISA.;Measurement of serum E2,. Timepoint: On the day the gonadotropins started, and on the day of the trigger with Deca in the follicular and luteal phase. Method of measurement: ELISA.;Measurement of serum LH. Timepoint: On the day the gonadotropins started, and on the day of the trigger with Deca in the follicular and luteal phase. Method of measurement: ELISA.;Measurement of serum FSH. Timepoint: On the day the gonadotropins started, and on the day of the trigger with Deca in the follicular and luteal phase. Method of measurement: ELISA.;The quantity of retrieved oocytes. Timepoint: Measuring in the first menstrual cycle and after taking ovulation-inducing drugs. Method of measurement: Ultrasouand system. | — |
Secondary
| Measure | Time frame |
|---|---|
| The amount of pregnancy and successful birth. Timepoint: After 9 months. Method of measurement: Number of successful pregnancies and live births. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFarnaz Montazeri
Iranian academic center for education culture and research
Outcome results
None listed