Effects of pilates training and turmeric supplementation on SIRT1, Klotho gene and Quality of life

Effects of 12 weeks of pilates training and turmeric supplementation on SIRT1, Klotho gene and Quality of life in middle-aged Overweight females

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180218038785N1

Enrollment

Registered

2018-03-15

Start date

2018-04-02

Completion date

Unknown

Last updated

2018-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aging.

Interventions

Intervention 1: Intervention group (training) : Participate in 12 weeks of Pilates training (3 sessions per week with intensity of 40 -70 % maximum heart rate). Intervention 2: Intervention group (sup

Eligibility

Sex/Gender

Female

Age

35 Years to 55 Years

Inclusion criteria

Inclusion criteria: Age range of 35 to 55 years Being Overweight( BMI: 25-30 kg/m²) Without regular physical activity No drug and supplementation Having menstrual period

Exclusion criteria

Exclusion criteria: illness allergy to spices Unwillingness or person's cooperation

Design outcomes

Primary

Measure	Time frame
Sirtuin1. Timepoint: Before and after the intervention (3 month later). Method of measurement: Sirtuin 1 content will be measured by using Human Sirtuin1 ELISA kit, made by Shanghay Crystal D company.;Serum Klotho gene. Timepoint: Before and after the intervention (3 month later). Method of measurement: Human Klotho ELISA kit, made by Shanghay Crystal D company.;Quality of life. Timepoint: Before and after the intervention (3 month later). Method of measurement: Quality of life questionare.	—

Measure

Time frame

Sirtuin1. Timepoint: Before and after the intervention (3 month later). Method of measurement: Sirtuin 1 content will be measured by using Human Sirtuin1 ELISA kit, made by Shanghay Crystal D company.;Serum Klotho gene. Timepoint: Before and after the intervention (3 month later). Method of measurement: Human Klotho ELISA kit, made by Shanghay Crystal D company.;Quality of life. Timepoint: Before and after the intervention (3 month later). Method of measurement: Quality of life questionare.

—

Secondary

Measure	Time frame
Weight. Timepoint: Before and after intervention (3 month later). Method of measurement: With Omron Digital Scale.;Body fat percent. Timepoint: Before and after intervention (3 month later). Method of measurement: Using body composition analyzer.;Fat-free mass. Timepoint: Before and after intervention (3 month later). Method of measurement: Using body composition analyzer.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRahele Dolgari

The University of Tabriz

R_Dolgari@yahoo.com+98 41 3289 4793

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026