Post-term Pregnancy. Post-term pregnancy
Conditions
Interventions
Intervention 1: Intervention group: Vaginal misoprostol (25 micrograms) in pregnant women and membrane stripping. Intervention 2: Control group: membrane stripping.
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Pregnant women with gestational age 39 weeks Primigravida Between 18 - 40 years old Singletone pregnancy Normal fetal heart rate Cephalic presentation (Vertex) AFI equal or more than 5 cm No history of medical or midwifery disorders Bishop score less than 8 Reactive NST Without uterine contractions
Exclusion criteria
Exclusion criteria: Macrosomia Sensitivity to PGs Uterin wall scar Preeclampsia or blood pressure more than 140/90 mmhg PROM Vaginal Bleeding IUGR fetus
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Delivery rate before 41th week of gestational age. Timepoint: 39th week, 40th week and then every other day. Method of measurement: newborn birth. | — |
Secondary
| Measure | Time frame |
|---|---|
| Admission time to 2nd stage interval. Timepoint: Admission time and stage 2. Method of measurement: time interval (hour).;First administration to delivery interval. Timepoint: 39th week, delivery time. Method of measurement: time interval (hour).;Duration of stage 2. Timepoint: full diatation , fetal delivery. Method of measurement: time interval (min).;Additional interventions. Timepoint: Delivery time. Method of measurement: additional doses of oxytocin and misoprostol.;Final route of delivery. Timepoint: delivery time. Method of measurement: normal vaginal delivery or cesarian section duo to documents.;Maternal complication. Timepoint: delivery time. Method of measurement: Any complication that has been registered in the case file for the mother.;Apgar score. Timepoint: first and 5th minutes after delivery. Method of measurement: apgaar score scale.;Meconial staining. Timepoint: delivery time. Method of measurement: observation at delivery time.;Gestational age at admission. Timepoint: Admission time. Method of measurement: gestational age according first trimester sonography.;Bishop score at admission. Timepoint: admission time. Method of measurement: according to bishop score scale.;Additional dose of misoprostol or oxytocin. Timepoint: admission to delivery. Method of measurement: calculating additional dose of misoprostol or oxytocin. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFarnaz Hadavi
Mashhad University of Medical Sciences
Outcome results
None listed