Systemic scleroderma. Systemic sclerosis [scleroderma]
Conditions
Interventions
Intervention group: autologous fat transfer.
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Patients fulfilling the “American college of Rheumatology” criteria for systemicsclerosis with facial involvement
Exclusion criteria
Exclusion criteria: Pregnant or breastfeeding; Patients with diffuse skin sclerosis who had insufficient fat harvesting; Recently diagnosed patients with SSc who had not clear face and oral involvement; Patients with history of neoplasia in the last 5 years; Who were taking prednisolone more than 10mg/d.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mouth opening capacity: maximal distance in cm between the upper and lower incisors. Timepoint: Baseline and 3 months after procedure. Method of measurement: Ruler.;Mouth handicap in systemic sclerosis (MHISS) scale. Timepoint: Baseline and 3 months after procedure. Method of measurement: 12-item questionnaire of MHISS.;Skin sclerosis score. Timepoint: At baseline and 3 months after procedure. Method of measurement: Rodnan skin score.;Skin elasticity. Timepoint: At baseline and 3 months after procedure. Method of measurement: Reviscometer. | — |
Secondary
| Measure | Time frame |
|---|---|
| Aesthetic effect. Timepoint: At baseline and 3 months after procedure. Method of measurement: Photography before and after procedure. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNikoo Mozafari
Shahid Beheshti University of Medical Sciences
Outcome results
None listed