Ulcerative colitis. Ulcerative colitis
Conditions
Interventions
Intervention 1: Intervention group:Curcumin supplement, 1500 milligram daily, 3 times per day ,500 milligram capsule each time, for 60 days. Karen Pharma & Food Supplement Co. Intervention 2: Control
Sponsors
Ahvaz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
17 Years to 70 Years
Inclusion criteria
Inclusion criteria: Ulcerative colitis, confirmed by histopathology The severity of the disease is mild to moderate Patients without current diagnosis of other inflammatory, autoimmune and inclusive disease( including cancer, kidney disease, rheumatoid arthritis, liver disease, AIDS, and cardiovascular disease) The age range is between 17-70 years Tendency to participate in the study No changes in the type and amount of drug in the past month The patient should not be pregnant or breastfeeding
Exclusion criteria
Exclusion criteria: The patient is in the acute phase of the disease Reluctance to continue cooperation in this research History of large gastrointestinal surgery (except appendectomy, Cholecystectomy and hemorrhoidectomy) Smoking, alcohol and drug abuse Patients with gallstones or any disorder of the gallbladder, bladder stones
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum hs-CRP. Timepoint: The beginning of the study- The end of the study. Method of measurement: ELISA.;Serum TNF-a. Timepoint: The beginning of the study- The end of the study. Method of measurement: ELISA.;Serum ESR. Timepoint: The beginning of the study- The end of the study. Method of measurement: Westergren's Method.;Stool frequency per day. Timepoint: The beginning of the study- The end of the study. Method of measurement: Mayo Score.;Frequency of rectal bleeding per day. Timepoint: The beginning of the study- The end of the study. Method of measurement: Mayo Score. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNarges Sadeghi
Ahvaz University of Medical Sciences
Outcome results
None listed