Effect of morphine in combination with paracetamol in postoperative analgesia

Comparative study of the analgesic effect of morphine and paracetamol in combination with ketorolac and paracetamol in open prostatectomy surgery

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180206038647N1

Enrollment

Registered

2018-03-18

Start date

2017-10-28

Completion date

Unknown

Last updated

2018-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Open prostatectomy. Erectile dysfunction following simple prostatectomy

Interventions

Intervention 1: Intervention group: received one mg / kg body weight of ketorolac plus 35 mg per kg of body weight paracetamol. Intervention 2: Control group: received 0.1 mg / kg body weight of morph

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: All candidate patients for open prostatectomy referring to Ali ibn Abi Talib (AS) hospital in Zahedan

Exclusion criteria

Exclusion criteria: Drug use, narcotic drugs or psychiatric drugs Renal failure Hepatic failure Gastrointestinal disease Opioid, ketrolac and paracetamol allergy Spinal anesthesia contraindication General anesthetic contraindication Failure of spinal anesthesia and switch to general anesthesia Respiratory depression while receiving a pump of pain

Design outcomes

Primary

Measure	Time frame
Severity of postoperative pain. Timepoint: 4, 8, 12, 24, 36 and 48 hours after surgery. Method of measurement: Visual Analogue Scale.;Sedation. Timepoint: 4, 8, 12, 24, 36 and 48 hours after surgery. Method of measurement: Ramssay score.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSiavash Jamalzehi

Zahedan University of Medical Sciences

Dr.jamalzehi@zaums.ac.ir+98 54 3329 5744

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026