A study of efficacy of mindfulness-based cognitive therapy in patients with treatment-resistant depression

A study of efficacy of mindfulness-based cognitive therapy in reducing ruminating, improving mindfulness and self-compassion in patients with treatment-resistant depression

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180205038630N1

Enrollment

Registered

2018-02-27

Start date

2018-03-21

Completion date

Unknown

Last updated

2018-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Resistant to depression. Neonatal cerebral depression

Interventions

Intervention group: For eight weeks in addition to antidepressants they also receive cognitive therapy based on mind-awareness..

Eligibility

Sex/Gender

All

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Lack of therapeutic response to enough doses of two antidepressants for an adequate period( after 18 weeks) Score 19 or higher in Beck depression inventory Having a diagnostic criterion for major depressive disorder Reading 9th grade education level to complete the questionnaire Having a minimum age of 18 and a maximum of 45 years

Exclusion criteria

Exclusion criteria: Having intense suicidal thoughts Need to be Hospitalization Failure to do homework related to treatment Affected by seasonal depression

Design outcomes

Primary

Measure	Time frame
Score in Self-Compassion Inventory (Short Form). Timepoint: At the beginning of the study, after the study (after the end of the intervention) and two months after the study. Method of measurement: Self-Compassion Inventory.;Mindfulness Questionnaire Score. Timepoint: At the beginning of the study, after the study (after the end of the intervention) and two months after the study. Method of measurement: Southampton Mindfulness Questionnaire for Consciousness.;Score in the rumination questionnaire. Timepoint: At the beginning of the study, after the study (after the end of the intervention) and two months after the study. Method of measurement: Ruminative Response Questionnaire.;Depression Score in Beck Questionnaire and Hamilton Grading Scale. Timepoint: At the beginning of the study, after the study (after the end of the intervention) and two months after the study. Method of measurement: Beck Depression Inventory and Hamilton's Grading Scale for Depression.	—

Measure

Time frame

Score in Self-Compassion Inventory (Short Form). Timepoint: At the beginning of the study, after the study (after the end of the intervention) and two months after the study. Method of measurement: Self-Compassion Inventory.;Mindfulness Questionnaire Score. Timepoint: At the beginning of the study, after the study (after the end of the intervention) and two months after the study. Method of measurement: Southampton Mindfulness Questionnaire for Consciousness.;Score in the rumination questionnaire. Timepoint: At the beginning of the study, after the study (after the end of the intervention) and two months after the study. Method of measurement: Ruminative Response Questionnaire.;Depression Score in Beck Questionnaire and Hamilton Grading Scale. Timepoint: At the beginning of the study, after the study (after the end of the intervention) and two months after the study. Method of measurement: Beck Depression Inventory and Hamilton's Grading Scale for Depression.

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Secondary

Measure	Time frame
Quality of Life Score. Timepoint: Study beginning, after study, two months after study. Method of measurement: Beck Depression Inventory.;Life expectancy score. Timepoint: Study beginning, after study, two months after study. Method of measurement: Beck Depression Inventory.;Changing the cost of treatment. Timepoint: Study beginning, after study, two months after study. Method of measurement: Beck Depression Inventory.	—

Measure

Time frame

Quality of Life Score. Timepoint: Study beginning, after study, two months after study. Method of measurement: Beck Depression Inventory.;Life expectancy score. Timepoint: Study beginning, after study, two months after study. Method of measurement: Beck Depression Inventory.;Changing the cost of treatment. Timepoint: Study beginning, after study, two months after study. Method of measurement: Beck Depression Inventory.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactGhazaleh Azar

Kermanshah University of Medical Sciences

ghazalehazar.8540@gmail.com+98 74 3246 3548

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026