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lung contusion in blunt trauma

Effect of Vitamin C and Vitamin E on Lung Contusion

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180205038627N1
Enrollment
80
Registered
2018-07-01
Start date
2016-04-08
Completion date
Unknown
Last updated
2018-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rib fracture, Hemothorax,? pneumothorax and lung contusion. Traumatic hemopneumothorax, initial encounter

Interventions

Intervention 1: Intervention group 1: Patients with injury severity score (ISS) 18±2 blunt chest trauma received intravenous vitamin E (1000 IU/mg), ABG parameters, serum cortisol, and CRP levels were

Sponsors

Kashan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: limited unilateral injury Being in serious to severer traumatic condition informed consent

Exclusion criteria

Exclusion criteria: Penetrative trauma , patients with opium addiction, COPD, asthma Glasgow Coma Scale (GCS), less than 13 receiving corticosteroids in the last 2 weeks history of chronic rheumatoid major associated trauma, pulmonary edema blood transfusion thromboembolic effects in long bone fracture ARDS pneumonia intervention such as brain,abdominal and major orthopedic surgery :pelvic, femur fracture

Design outcomes

Primary

MeasureTime frame
ICU stay in groups 1,2, vs control not significant, ICU stay in group 3(3.5 ±0.5) vs control(5.2 ± 1.67) was significant. Timepoint: Measurement of day time during ICU stay. Method of measurement: time.;Measured carbon dioxide pressure in groups 3, when compared to other groups, was significant. Timepoint: were determined at baseline, 24 hours and 48 hours after the intervention. Method of measurement: ABG from arterial vessel.;Measured PH and Pao2. Timepoint: were determined at baseline, 24 hours and 48 hours after the intervention. Method of measurement: ABG from arterial vessel.;Plasma cortisol and CRP levels between groups after the intervention that was not significant. Timepoint: were determined at baseline, 24 hours and 48 hours after the intervention. Method of measurement: from infra venous line.

Countries

Iran (Islamic Republic of)

Contacts

Public Contact?Abdoulhossein Davoodabadi

Kashan University of Medical Sciences

davoodabadi_ab@kaums.ac.ir+98 31 5554 3154

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026