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The short-term outcomes of Ticagrelor versus Clopidogrel in patients with myocardial infarction

Comparison the short-term outcomes of Ticagrelor versus Clopidogrel treatment in patients with myocardial infarction undergoing Percutaneous Coronary Intervention

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180205038626N9
Enrollment
128
Registered
2021-07-13
Start date
2021-08-23
Completion date
Unknown
Last updated
2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute myocardial infarction. Other current complications following acute myocardial infarction

Interventions

Intervention 1: Control group: Clopidogrel group: patients will receive 600 mg of clopidogrel as a loading dose and then in addition to aspirin 81 mg daily, clopidogrel 75 mg daily tablet will be pres

Sponsors

Rasht University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age 18 years and older Chest pain that lasts more than 20 minutes and no response to nitroglycerin Patients with PCI were underwent PCI less than 12 hours from the onset of symptoms. The ST segment rises more than 1 mm in at least two or more limb leads. The ST segment is more than 2 mm high in two or more precordial leads.

Exclusion criteria

Exclusion criteria: Cardiogenic shock in the form of systolic blood pressure less than 90 to 60 mm Hg and did not respond to hydration therapy Thrombolysis in the last 24 hours Recent anticoagulant therapy or recent use of P2Y12 antagonist Contraindications to aspirin, clopidogrel and ticagrelor History of coronary artery bypass grafting in recent year Patient dissatisfaction

Design outcomes

Primary

MeasureTime frame
Thrombosis. Timepoint: 3 months later. Method of measurement: Clinical signs and laboratory tests.;Stroke. Timepoint: 3 months later. Method of measurement: CT scan.;Myocardial Infarction. Timepoint: 3 months later. Method of measurement: Electrocardiography, Echocardiography.

Secondary

MeasureTime frame
Death. Timepoint: 3 months later. Method of measurement: Phone call with the patient.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZahra Ahmadnia

Rasht University of Medical Sciences

zahmadnia@gums.ac.ir+98 13 3361 8177

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026