Comparison of the Efficacy of Platelet-Rich Plasma (PRP) and Lidocaine Injections at Trigger Points in Patients with Cervical Myofascial Pain Syndrome.

Comparison of the Efficacy of Platelet-Rich Plasma (PRP) and Lidocaine Injections at Myofascial Trigger Points in Patients with Cervical Myofascial Pain Syndrome: A Randomized Controlled Trial

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180205038619N4

Enrollment

Registered

2025-10-05

Start date

2025-07-20

Completion date

Unknown

Last updated

2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cervical Myofascial Pain Syndrome. Chronic pain, not elsewhere classified

Interventions

Intervention 1: Intervention group: Platelet-rich plasma (PRP) will be injected into trigger points in an amount of 2-3 cc at the first visit to the trigger points of the trapezius muscles on both sid

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1.Adults (18 to 60 years old) diagnosed with cervical myofascial pain syndrome (MPS) based on clinical criteria. 2.The presence of myofascial trigger points (MTrPs) in the upper trapezius muscle or neck muscles. Pain duration = 3 months. Pain score on visual analog scale (VAS) = 4 Informed consent.

Exclusion criteria

Exclusion criteria: 1. History of surgery or trauma to the cervical spine. 2. Rheumatic or neurological disorders affecting the neck. 3. Contraindications for injection (bleeding disorders, infection at the injection site, pregnancy). 4. Use of systemic steroids or anticoagulants.

Design outcomes

Primary

Measure	Time frame
The severity of pain. Timepoint: 2 week, one month, 3 months, six months after. Method of measurement: Visual Analog Scale (VAS).;Neck Disability Index. Timepoint: 2 week, one month, 3 months, six months after. Method of measurement: Questionnaire used to assess disability caused by neck pain.;Neck range of motion. Timepoint: 2 week, one month, 3 months, six months after. Method of measurement: Neck range of motion in different directions.	—

Measure

Time frame

The severity of pain. Timepoint: 2 week, one month, 3 months, six months after. Method of measurement: Visual Analog Scale (VAS).;Neck Disability Index. Timepoint: 2 week, one month, 3 months, six months after. Method of measurement: Questionnaire used to assess disability caused by neck pain.;Neck range of motion. Timepoint: 2 week, one month, 3 months, six months after. Method of measurement: Neck range of motion in different directions.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactKatayoun Moradi

Iran University of Medical Sciences

katayounmoradi69@gmail.com009802164351

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026