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Evaluation of the effectiveness of TDCS (Transcranial Direct Current Stimulation) in the treatment of prolonged decreased of sense of smell in patients with Covid-19

Evaluation of the effectiveness of TDCS (Transcranial Direct Current Stimulation) in the treatment of hyposmia in patients with Covid-19

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180205038619N2
Enrollment
10
Registered
2021-08-30
Start date
2021-09-10
Completion date
Unknown
Last updated
2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

covid-19. Coronavirus infection, unspecified

Interventions

The intervention group will receive a direct current of 2 mA for 20 minutes. In all patients, the anode electrode is located on the left DLPFC region and the cathode electrode is located on the right

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age between 18 and 60 years Loss of sense of smell after Covid-19 (anosmia that has not improved for more than a month after the onset of symptoms and with routine treatment) Decreased of sense of smell after Covid-19 (anosmia that has not improved for more than a month after the onset of symptoms and with routine treatment)

Exclusion criteria

Exclusion criteria: Pregnancy Seizures or family history of seizures Implanted metal devices such as pacemakers, metal plate and wire History of brain surgery

Design outcomes

Primary

MeasureTime frame
Olfactory sensitivity. Timepoint: Patients are assessed before the intervention and one week after 4 sessions of TDCS. Method of measurement: Participants' olfactory sensitivity will be measured by the Smell Identification Test (SIT) . In this method, 24 Iranianized odor such as rose, caffeine, saffron, etc. will be used and a score of 24 will be given, with a score of 19 to 24 being considered the normal range. A score of 14 to 18 is mild microsmia, a score of 10 to 13 is severe microsmia, and a score of 0 to 9 is anosmia.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactKatayoun Moradi

Iran University of Medical Sciences

katayounmoradi69@gmail.com+98 21 8214 1229

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026