Effect of prednisolon acetete drop on pupil dilation and ocular pain after cataract surgery

Evaluation the effect of topical prednisolon acetate 1% on the pupillary diameter and ocular pain after uncomplicated cataract surgery in diabetic and non diabetic patients

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180205038617N1

Enrollment

Registered

2018-04-09

Start date

2017-03-13

Completion date

Unknown

Last updated

2018-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Effect of topical dipped prednisolone acetate 1% on pupil dilatation and pain after uncomplicated cataract surgery. Age-related incipient cataract

Interventions

Intervention 1: Intervention 1: Non-diabetic patients who recieve topical prednisone acetate 1% drop, every six hours, 24 hours before surgery. Patients are advised to shake the bottle before using.

Eligibility

Sex/Gender

All

Age

40 Years to No maximum

Inclusion criteria

Inclusion criteria: In non- diabetic group: Patients over 40 years old with cortical cataract, posterior subcapsular or grade 2 to 3 nuclear sclerosis that have indication of phacoemulsification surgery with general anesthesia In diabetic group: Patients over 40 years old with cortical cataract, posterior subcapsular or grade 2 to 3 nuclear sclerosis that have pseudoexfuliation or non proliferative diabetic retinopathy and have indication of phacoemulsification surgery with general anesthesia

Exclusion criteria

Exclusion criteria: History of previous intraocular surgery collagen vascular disease history of previous or current topical steroids, alphablocker or antiglaucoma medication history of previous or current systemic steroid use history of uveitis mature cataract

Design outcomes

Primary

Measure	Time frame
Horizontal pupilary diameter. Timepoint: The diameter of the pupilary horizontal diameter is measured at the beginning and at the end of the operation using caliber and is divided into two groups up and down six millimeters. Method of measurement: Caliber.;The score of post-operative pain which is measured by Visual Analog Scale for pain questionnaire. Timepoint: 24 hours after surgery. Method of measurement: Score of Visual Analog Scale for pain questionnaire.	—

Measure

Time frame

Horizontal pupilary diameter. Timepoint: The diameter of the pupilary horizontal diameter is measured at the beginning and at the end of the operation using caliber and is divided into two groups up and down six millimeters. Method of measurement: Caliber.;The score of post-operative pain which is measured by Visual Analog Scale for pain questionnaire. Timepoint: 24 hours after surgery. Method of measurement: Score of Visual Analog Scale for pain questionnaire.

—

Secondary

Measure	Time frame
Post operative photophobia. Timepoint: 24 hours after surgery. Method of measurement: Visual Analogue Scale for pain questionnaire.;Foreign body sensation. Timepoint: 24 hours after surgery. Method of measurement: Visual Analogue Scale for pain questionnaire.;Itching. Timepoint: 24 hours after surgery. Method of measurement: Visual Analogue Scale for pain questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHoseinzadeh Abolfazl

Mashhad University of Medical Sciences

Hoseinzadeha1@mums.ac.ir+98 51 3840 2924

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026