chronic migraine. Migraine without aura [common migraine]
Conditions
Interventions
Intervention 1: BOTOX injection for chronic migraine headache patients by FTP method. Intervention 2: Intervention group: BOTOX injection for chronic migraine headache patients by FSFD method.
Sponsors
Rafsanjan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients who have at least 15 days headache that maintain for 4 hour or more Patients who had no improvement in severity & frequency of headaches by using prophylactic drug agents like that Beta blockers, CCB, anti convulsive drugs & anti depressant
Exclusion criteria
Exclusion criteria: Pregnancy History of BOTOX injection or other Botulinum serotypes Neuromuscular junction disease Psychologic disorders that have negative impact on clinical trial Beck severity scale of depression more than 24 Primary or secondary headaches due to another reasons Complicated migraine Drug sensivity Coagulopathy Infection of injection skin site
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Frequency of migraine headache attacks. Timepoint: The days 0, 30, 60, 90, 120 after injection. Method of measurement: Migraine diary chart. | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life improvement. Timepoint: Synchronous to first variable outcome evaluation. Method of measurement: Quality of life questionnaire approved by WHO. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr.Fekri Mohadese
Rafsanjan University of Medical Sciences
Outcome results
None listed