Melasma. Chloasma
Conditions
Interventions
Intervention 1: Intervention group 1: Right side face treated with intradermal 4 mg/ml tranexamic acid every other week for 12 weeks. Intervention 2: Intervention group 2: Right side face treated with
Sponsors
Ahvaz University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: Women at the range of 18 to 50 years old with symmetrical bilateral melasma who signature the letter of satisfaction
Exclusion criteria
Exclusion criteria: Pregnant and lactating women Oral contraceptive pill consumption in 12 months ago during RCT History of coagulopathy and thrombotic disorder Anticoagulant and antiepileptic drug consumption Sensitivity to tranexamic acid History of treatment for melasma during 1 month ago Active facial herpes simplex virus infection Facial wart `
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Melasma area and severity index. Timepoint: Melasma area and severity index measured at base of trial and 4, 8, 12 and 22. Method of measurement: Melasma area and severity index score. | — |
Secondary
| Measure | Time frame |
|---|---|
| Patients satisfaction. Timepoint: Measuring of patient satisfaction in 8, 12 and 22 week of trial. Method of measurement: Satisfaction percentage questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMaryam Zeynalie
Ahvaz University of Medical Sciences
Outcome results
None listed