Agitated Patients. Violent behavior
Conditions
Interventions
Intervention 1: Intervention group: Ketamine 4mg/kg (50 mg/ml, made in ROTEXMEDICA Co.). If aggression is not controlled the second dose is injected in half of the initial dose(2mg/kg). If is not yet
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: All the patients who intended to damage themselves or others Altered mental status score (AMSS) +2 or +3 Required physical restraint and parenteral sedation
Exclusion criteria
Exclusion criteria: serious physical illness History of heart disease pregnancy drug dependence treatment with a benzodiazepine or neuroleptic within the previous 24 hours Ketamine and Haloperidol contraindications
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Aggression control. Timepoint: Every 5 minutes. Method of measurement: altered mental status score. | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effects. Timepoint: Every 15 minutes. Method of measurement: Physical exam.;Frequency of repeat dosing. Timepoint: After 6 hour. Method of measurement: Physical exam.;Vital signs. Timepoint: Every 5 minutes. Method of measurement: Physical exam.;Satisfaction. Timepoint: After 6 hour. Method of measurement: Questionnaire.;Intubation. Timepoint: After 6 hour. Method of measurement: Counts. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFarhad Heydari
Esfahan University of Medical Sciences
Outcome results
None listed