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Effect of topical ketamine on pain relief

Comparison of the effectiveness of lidocaine-perilocaine cream with topical ketamine in reducing local pain in patients

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180129038549N2
Enrollment
75
Registered
2018-02-20
Start date
2017-10-23
Completion date
Unknown
Last updated
2018-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

...

Interventions

Intervention 1: Patients are treated with EMLA cream. A 5%EMLA cream is a combination of 2.5% lidocaine and 2.5% perlocaine produced by Iranian chemistry company Iran. For each patient, 2 grams of 4 ×

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: All adult patients referred to the emergency department of al-Zahra and Kashani hospitals Need for Peripheral Intravenous Cannulation Alert

Exclusion criteria

Exclusion criteria: The presence of visual, mental and verbal disorders Opioids addiction Sensitivity to anesthetic drugs Patients in a life-threatening condition Analgesic drug addict(More than 4 times a week)

Design outcomes

Primary

MeasureTime frame
The severity of pain. Timepoint: After intravenous cannulation. Method of measurement: Visual Analogue Scale.

Secondary

MeasureTime frame
Time to start anesthetic effect. Timepoint: To an hour of exposure. Method of measurement: Time (minute).;Drug side effects such as redness, whitening and skin blemishes. Timepoint: Until the time of discharge. Method of measurement: Observation.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarhad Heydari

Esfahan University of Medical Sciences

drfarhadheydari@gmail.com+98 31 3776 9818

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026