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Effect of high-pressure nasal cannula and conventional oxygen treatment in Covid-19

Comparison of the effect of high-pressure nasal cannula and conventional oxygen treatment in Covid-19 patients referred to the emergency department

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180129038549N15
Enrollment
66
Registered
2021-12-20
Start date
2021-12-22
Completion date
Unknown
Last updated
2022-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Respiratory failure. Condition 2: Covid-19. Acute respiratory failure Coronavirus infection, unspecified

Interventions

Intervention 1: Intervention group: Covid-19 patients admitted to the emergency department are first treated with nasal oxygen for at least 15 minutes and then, if they do not improve and the oxygen l

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Oxygen saturation less than 90% despite receiving nasal oxygen = 3 L/min or respiratory rate more than 24 breaths per minute The diagnosis of Covid-19 is confirmed based on PCR or lung HRCT Alert patients

Exclusion criteria

Exclusion criteria: Unstable hemodynamics Obesity Hypoventilation Syndrome Respiratory failure due to pulmonary edema Patients who do not tolerate the use of high pressure oxygen Cases in which emergency intubation is required Pregnant women

Design outcomes

Primary

MeasureTime frame
Increased blood oxygen saturation. Timepoint: One hour after treatment. Method of measurement: Pulse oximetry.

Secondary

MeasureTime frame
Vital signs include heart rate and respiratory rate and systolic and diastolic blood pressure. Timepoint: One hour after treatment. Method of measurement: Manometer( pressure gauge) and count.;Intubation rate. Timepoint: Until discharge from the hospital. Method of measurement: Count.;Intensive care unit admission rate. Timepoint: Until discharge from the hospital. Method of measurement: Count.;Mortality rate. Timepoint: Until discharge from the hospital. Method of measurement: Count.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarhad Heydari

Esfahan University of Medical Sciences

drfarhadheydari@gmail.com+98 31 3776 9818

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026