Evaluation of the effect of painless spray in reducing local pain

Comparison of the effect of Pain Less Spray and cold compress on reducing pain caused by venipuncture in patients admitted to the emergency room

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180129038549N13

Enrollment

200

Registered

2021-12-11

Start date

2021-12-01

Completion date

Unknown

Last updated

2022-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Procedural pain.

Interventions

Intervention 1: Intervention group: A puff of painless spray is used ten minutes before venipuncture of the upper limb at the site of venipuncture. The intravenous cannulation is inserted in back of t

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: All adult patients referred to the emergency department of al-Zahra and Kashani hospitals Need for Central Venous Catheter Insertion Alert Stable vital signs

Exclusion criteria

Exclusion criteria: The presence of visual, mental and verbal disorders Sensitivity to anesthetic drugs Sensory or motor disorder of the upper extremities

Design outcomes

Primary

Measure	Time frame
The severity of pain. Timepoint: After intravenous cannulation. Method of measurement: Numeric Analogue Scale (NAS).	—

Secondary

Measure	Time frame
Drug side effects such as redness, whitening and skin blemishes. Timepoint: Until the time of discharge. Method of measurement: Standard questionnaire form.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarhad Heydari

Esfahan University of Medical Sciences

drfarhadheydari@gmail.com+98 31 3786 8804

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026