Chronic nephritic syndrome. Chronic nephritic syndrome
Conditions
Interventions
Intervention 1: Intervention group: Mycophenolate mofetil with a dose of 1 g every 12 hours for 6 months and prednisolone 0.5 mg/kg/d for 3 months. Intervention 2: Control group: Oral cyclophosphami
Sponsors
Ahvaz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients with nephrotic syndrome with more than 4 gr / d of proteins in 24-hour urine changes in GFR by increase more than 30% without a known cause in serum creatinine level patients with severe and disabling symptoms associated with nephrotic syndrome
Exclusion criteria
Exclusion criteria: systemic disease malignancy active infection pregnancy unstable angina pectoris type I and type II diabetes clinical evidence of renal vein thrombosis acute gastric ulcer or gastrointestinal disease that disturbs the absorption of oral medications
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Urine protein. Timepoint: Before intervention and after 2, 4 and 6 month of intervention. Method of measurement: Urine biochemistry test.;Albumin. Timepoint: Before intervention and after 2, 4 and 6 month of intervention. Method of measurement: Urine biochemistry test.;Blood cholesterol. Timepoint: Before intervention and after 2, 4 and 6 month of intervention. Method of measurement: Blood biochemistry test.;Blood creatinin. Timepoint: Before intervention and after 2, 4 and 6 month of intervention. Method of measurement: Blood biochemistry test. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Shahla Ahmadi Halili
Ahvaz University of Medical Sciences
Outcome results
None listed