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Effect of Colchicine in improvement of myocardial infarction patients undergoing therapeutic intervention

Evaluation of effects of Colchicine on corrected Thrombolysis In Myocardial Infarction (TIMI) frame in ST segment elevation myocardial infarction patients undergoing primary percutaneous coronary intervention (PPCI)

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180127038515N1
Enrollment
60
Registered
2018-03-19
Start date
2017-04-21
Completion date
Unknown
Last updated
2018-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ST segment elevation myocardial infarction. ST elevation (STEMI) and non-ST elevation (NSTEMI) myocardial infarction

Interventions

Intervention 1: Intervention group: administration of 2mg Colchicine. Intervention 2: Control group: administration of 2mg placebo tablet.

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: stability for at least previous 6 months ability for participation in followups consent for enter in the study

Exclusion criteria

Exclusion criteria: contraindication of Colchicine consumption infectious disorder or active inflammatory disorder or known malignancy current treatment by Corticosteroid or other anti-inflammatory drugs known sensitivity to Colchicine or current treatment by Colchicine severe renal failure (GFR<30) liver failure cardiac arrest ventricular fibrillation or symptomatic cardiogenic shock stent thrombosis occurrence of angina 48 hours before infarction previous myocardial infarction left main coronary artery or left circumflex occlusion existence of metal implant pregnancy

Design outcomes

Primary

MeasureTime frame
Corrected TIMI frame count index. Timepoint: before starting PCI, after doing PCI. Method of measurement: By using angiography device.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSamaneh Hassanzadeh Avval

Mashhad University of Medical Sciences

s.hassanzadeh1@gmail.com+98 51 3854 3031

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026